The week-long police initiative saw officers carrying out sniffer dog searches in pubs and clubs across the region.
A number of targeted house searches were also carried out, which saw the seizure of illegal drugs as well as two vehicles under the Proceeds of Crime Act.
Fifteen people were arrested – aged between 14 and 41-years-old – in the operation for crimes including the possession of class A and B drugs, money laundering and burglary.
Sergeant Dan Hadfield from the Buxton Operational Support Team said: “Whilst the initial strike week has come to an end, we will continue to target the use and supply of drugs across the division.
“I’d like to urge the public to report suspected drugs activity to police or Crimestoppers as we do act on the intelligence that you provide.”
The team also spoke to young people to offer advice on drug and alcohol use, along with reassuring residents that positive action will be taken against dealers.
Call police on 101 if you have information on drugs in the community.