A fundraising target of £1,000 has been set by staff at the Railway Hotel in Buxton who are looking to support the Christie Hospital.
A sponsored leg wax and a head shave are among the events set to take place during the evening of Saturday, March 17.
There will also be a raffle, with local businesses lending their support by donating prizes, a disco from 7.30pm and a late bar.
Matthew Stone, Assistant Manager said: “We have not done anything like this before but are hoping to raise at least £1,000.”
The charity was chosen as a number of staff members had family who had received treatment at the Christie.