A Honda motorhome and a Ford Fiesta collided on the A619 in Baslow between the Robin Hood Inn pub and the Golden Gates roundabout at about 8.30am.
A Derbyshire police spokesman said: “Four people were injured, two seriously.
“They have been taken to the Northern General Hospital in Sheffield.”
The road, which was closed to allow for the removal of debris and fluid, has now reopened.
Most Popular
-
1
'World’s best sweet shop’ contents up for auction as Peak District owner sells everything to start new adventure
-
2
Buxton B&B set to become children's home if High Peak council approves plans
-
3
Buxton man looking to find new home for WW1 and WW2 medals
-
4
Air ambulance scrambled to crash on Derbyshire’s Snake Pass – amid fears of serious injuries to casualty
-
5
Fire service renews safety warning as new heatwave looms in Derbyshire
The road closure caused widespread congestion in the area.